Scientists contain the sperms that elevate the X and Y chromosomes in a scrutiny that could, at some point, eventually contain “mammoth” implications for the choice of animal intercourse, including other people.
The sperm raises an X or Y chromosome, which helps resolve offspring intercourse in most mammals. In the original, X- and Y-bearing sperm are swimming in semen in equal numbers, which explains why humans, as an instance, are made up of more or less males and females.
However, because X and Y sperm carry half of the identical proteins so that the fetus can assemble in most cases, there are no identified markers that differentiate between the two. For years, scientists have been developing a safe technique for dividing these reproductive organs. cells in diverse species, as this could occasionally help make a different relationship between cattle and other people, however they were unsuccessful.
Now the authors of an article printed in the magazine PLOS Biology they mutter that they have found markers that exist or are no longer sperm that carry the X or Y chromosome in mice. Scientists have come across an X-chromosome protein in the X-sperm, and fragile to separate them from reproductive cells that carry Y. They fry their methodology for litter prices consisting primarily of a sexual relationship.
Examine the co-creator Professor Masayuki Shimada from Hiroshima University said Newsweek no doubt an escape for your comparison. “In dairy farms, the price of female cows is higher than male cows, because milk is fully produced by the female cow. In case beef meets fabrication, the rise rate is blueprint increased in male after castration than in female. So the price of male calves is higher than female calves. ”
Consultants who did not work on the comparison were annoyed by the findings but, although concerned, need to be replicated in diverse species before continued depletion.
Peter Ellis, professor of molecular genetics and replica at the University of Kent, said Newsweek"If this scrutiny could be replicated by chance, by chance, and replicated – and, suppose, if it is valid in diverse species than rats – the implications would be enormous for both animal and human synthetic insemination."
He asked why the researchers did not replicate the work on diverse species, but added, "I doubt if this happens by chance it happens much sooner than anyone has a survey!"
The work undoubtedly leaves it to the intercourse resolution, however fearless "which is totally conjecture for the moment and remains to be tested."
David Elliott, a professor of genetics at the University of Newcastle, who no longer worked on the scrutiny Newsweek: “This scrutiny provides us with significant thinking about how sperm are produced. Through meiosis – the cell division that produces sperm, the X chromosome was thought to be "turned off," with specific genes on diversified chromosomes replacing those on X, and these diversified genes would be shared between X and Y with sperm. . Throughout the later stages of sperm manufacturing, many genes are turned off anyway, as the sperm head becomes miniaturized. This scrutiny suggests that, despite this, the X chromosome may rest up to the price of an obvious sperm.
Elliott said he was surprised "that the two sets of sperm want to be so biochemically diverse as they come together so carefully together."
“If X and Y with human sperm contain connected differences, then in theory they will be separated into a connected methodology. However, sperm receptors could, by chance and by chance, be in most cases diversified across species, so it is no longer possible for this to occasionally work, and there would be some important ethical and safety issues sooner than any other. application. for other people. "
James Turner, who leads the Laboratory of Chromosomal Intercourse Biology at the Francis Crick Institute, said Newsweek: "The discovery of a protein that fully marks X-sperm is certainly impressive, so the precedence of stopping undoubtedly will be to replicate that discovery and understand why this protein proves the exception to the guideline."
Charlotte Douglas, a PhD student at the Francis Crick Institute's Interchange Chromosome Biology lab, said Newsweek Existing systems for classifying bovine sperm are extremely efficient.
"In addition, an intensive overview of offspring fertility / viability generated after chemical sperm inhibition, specifically in agricultural species, deserves to be evaluated," she said.